Gabapentin is an anti-epileptic drug of a new generation that increases the gamma-aminobutyric acid (GABA) levels, it is structurally related to the neurotransmitter GABA, by the addition of a cyclohexyl group to its backbone, but does not interact with GABAA or GABAB receptors of GABA uptake carriers of brain.
Gabapentin interacts with a high affinity-binding site in brain membranes, which is an auxiliary subunit of voltage-sensitive calcium ion channels. Gabapentin is not appreciably metabolized in the body and most of the dose is excreted unchanged in the urine. Peak plasma concentrations are usually achieved within 3 hours and elimination half-life is about 5 to 7 hours.
In known hypersensitivity to any of the ingredients.
The most frequently reported adverse reactions are somnolence, backache, dizziness, fatigue, headache, nausea and vomiting.
The following instructions apply unless otherwise prescribed by the physician:
Conventin capsule should be administered two hours after the intake of antacids.
Conventin 100mg: Box of 1 or 2 strips, each of 10 capsules.
Conventin 400mg: Box of 1 or 2 strips, each of 10 capsules.